What Is the Connection of Sickle Cell Anemia and Malaria? Find Out Below!

What Is the Connection of Sickle Cell Anemia and Malaria? Find Out Below!

Do sickle cell anemia and malaria have a correlation? This question may be yours which have been popping in your mind for a long time. Sickle cell anemia is known as genetic disease. This disease modifies the structure of hemoglobin. The hemoglobin is the oxygen which carries protein the red blood cells. The altered hemoglobin which is not carrying oxygen may bunch with the deoxygenated hemoglobin. The deoxygenated hemoglobin deforms red blood cells and causes the blood to mass over the body. A specific gene HBB contains a protein which is known beta hemoglobin. The beta hemoglobin creates the sickle-shaped. This disease is commonly found in the America where the occurrence of malaria is high and it is caused by the sickle cell anemia.

When a person is ready to suffer a sickle cell disease. the red blood cell is more likely shape a sickle. This sickle cell leads to other diseases such as anemia, strokes, and lungs problems. In addition, when this disease leads to the sickle cell of anemia, it may have some effects to the malaria parasite. This disease is inherited disorder when a person has this disease from both his parents. The disease will develop gradually and die early. In contrast with the person who only gets the gene from one of both his parents. He may have a few of sickle-shaped of the blood.

sickle cell anemia and malaria
sickle cell anemia and malaria distributions

How is the sickle cell of anemia and malaria linked?

Read More : How to Treat Sickle Cell Anemia

There is a correlation which shows that the sickle cell can reduce the growing of malaria parasites especially for the people who lives in the endemic area such as African. The epidemic is higher to the African lowlands than the highland. Here are the correlation of the sickle cell anemia and malaria.

sickle cell anemia and malaria

  1. When the malaria parasite starts to live in the bloodstream of somebody which has sickle cell trait. The sickle cell breaks down and blocks the parasite. This condition makes the malaria parasite will be unable to continue its development. In other words, the malaria parasite is not able to survive.
  2. The hemoglobin is the need for the malaria parasite to grow. the sickle cell traits release the beta hemoglobin which prevents the growth of the malaria parasite.
  3. The malaria parasite needs potassium to grow. However, the less of potassium which is the result of the low oxygen of the sickle cell anemia and malaria parasite cannot continue its growth.
  4. Meanwhile, people with sickle cell disease has red blood cells with very low of the oxygen. when the malaria parasite enters the bloodstream. it reduces the oxygen even more. this condition leads to a destruction of its life.

The relationship between the sickle cell anemia and malaria is irrefutable. we also understand that the malaria parasite grows in the red blood cells. the sickle red blood cells are alleged to reduce and destruct the malaria parasite. Since, the sickle cells have beta hemoglobin, low oxygen, and do not produce potassium, and these things are the important things needed by the malaria parasite to grow up.!

How to Treat Sickle Cell Anemia

How to Treat Sickle Cell Anemia

How to Treat Sickle Cell Anemia

While it can be cured, learning how to treat sickle cell anemia is very important. It can be the difference between life and death for very small children with it. Effective treatment can also help people to live as normal of a life as possible in spite of their health condition. Today, we know more about sickle cell anemia than ever before so we have the means to effectively treat it.

Controlling the Pain

Individuals with sickle cell anemia often suffer from a great deal of pain. This can make it very hard for them to work, to care for their family, or even to get through normal daily activities. Pain medications are often necessary to make the individual more comfortable. Such medication will need to be taken daily for the best results. The doctor will have to determine the right medication as well as the dose of it for each individual case. For mild cases, over the counter pain medications may be sufficient.

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One type of pain medication offered is called Hydroxyurea and it is generally only for individuals that have a very serious sickle cell anemia diagnosis and they are at least 18 years of age. However, there are some serious side effects with it. For example it may increase the risk of someone developing leukemia or tumors after extended use.

How to Treat Sickle Cell Anemia

Infections are common with sickle cell anemia, so the form of medication that is offered has to be effective for preventing that from occurring too. Infections can cause permanent damage in the body which is why they are so dangerous and need to be intercepted. When an infection is detected, a form of medication known as antibiotics must be taken to destroy it. The antibiotics may need to be taken for a period of time that lasts from 7 to 10 days.

Health Assessment

Preventing serious problems for individuals with sickle cell anemia is very important. A regular health assessment is important to the overall care. Vision loss and eye damage are common for people with sickle cell anemia. Checking the eyes at least every six months is very important.

Stroke is another serious health problem associated with sickle cell anemia. Today there are tests that allow for people to be assessed when it comes to their risk of a stroke. In many medical facilities children start to get these types of tests when they are only about 2 years of age.

How to Treat Sickle Cell Anemia

Blood Transfusions

Among the methods for hoe to treat sickle cell anemia, the use of blood transfusions is used. There are safeguards in place to make sure the blood used is safe and it is clean. Most experts believe that these types of blood transfusions at regular intervals can reduce the risk of a stroke for patients with sickle cell anemia.

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One of the problems though with blood transfusions is that they can introduce too much iron into the body. The use of a type of medication called Deferasirox is often used to prevent that. When a person has too much iron in the body, vital organs can end up being damages so this needs to be closely monitored.

Bone Marrow Transplants

One of the most effective forms of treatment for sickle cell anemia is a bone marrow transplant. How to treat sickle cell anemia with it though can be complicated to fully understand. There has to be a very good match of donor bone marrow to conduct the transplant. This can be parents or siblings but very rarely is it every from a complete stranger. Still, there have been drives where people are asked to come be tested to see if they would be a good match for someone in need.

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